Articles with "bidirectional mendelian" as a keyword



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Association between COVID‐19 and telomere length: A bidirectional Mendelian randomization study

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Published in 2022 at "Journal of Medical Virology"

DOI: 10.1002/jmv.28008

Abstract: Several traditional observational studies suggested an association between COVID‐19 and leukocyte telomere length (LTL), a biomarker for biological age. However, whether there was a causal association between them remained unclear. We aimed to investigate whether… read more here.

Keywords: telomere length; covid; ltl; association covid ... See more keywords
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Vitamin D, prediabetes and type 2 diabetes: bidirectional Mendelian randomization analysis

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Published in 2019 at "European Journal of Nutrition"

DOI: 10.1007/s00394-019-01990-x

Abstract: Background Vitamin D deficiency is associated with glycemic dysregulation in many observational studies. However, the causality between them has not been fully established, especially in Asian origin. We used bidirectional Mendelian randomization (MR) analysis to… read more here.

Keywords: randomization analysis; mendelian randomization; bidirectional mendelian; type diabetes ... See more keywords
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Frailty and cardiometabolic diseases: a bidirectional Mendelian randomisation study.

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Published in 2022 at "Age and ageing"

DOI: 10.1093/ageing/afac256

Abstract: BACKGROUND Frailty is strongly associated with cardiometabolic diseases in observational studies. However, whether the observed association reflects causality requires clarification. We performed a bidirectional Mendelian randomisation (MR) study to assess the causal relationship of frailty,… read more here.

Keywords: randomisation study; mendelian randomisation; frailty; bidirectional mendelian ... See more keywords
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Is Vitamin D Deficiency the Cause or the Effect of Systemic Lupus Erythematosus: Evidence from Bidirectional Mendelian Randomization Analysis

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Published in 2022 at "Journal of Immunology Research"

DOI: 10.1155/2022/8689777

Abstract: Background Vitamin D deficiency is common in patients with systemic lupus erythematosus (SLE). Observational studies have reported that it is associated with SLE. In this bidirectional Mendelian randomization (MR) study, we explored the genetic association… read more here.

Keywords: effect; bidirectional mendelian; vitamin deficiency; vitamin ... See more keywords
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Educational attainment and offspring birth weight: A bidirectional Mendelian randomization study

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Published in 2022 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2022.922382

Abstract: Background: The association between educational attainment (EA) and offspring birth weight (BW) has been reported by several traditional epidemiological studies. However, evidence for this association tends to be mixed and confounded. This study aimed to… read more here.

Keywords: offspring birth; educational attainment; birth weight; bidirectional mendelian ... See more keywords
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Assessing the causality between thyroid and breast neoplasms: A bidirectional Mendelian randomization study

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.973161

Abstract: Aim This study aimed to evaluate the association between thyroid neoplasms (TN) and the risk of developing breast neoplasms (BN) by assessing data on single nucleotide polymorphisms (SNPs) obtained from the Deutsches Krebsforschungszentrum (DKFZ) and… read more here.

Keywords: mendelian randomization; breast; breast neoplasms; association ... See more keywords