Bidirectional nucleolar dysfunction in C9orf72 frontotemporal lobar degeneration
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DOI: 10.1186/s40478-017-0432-x
Abstract: An intronic GGGGCC expansion in C9orf72 is the most common known cause of both frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). The repeat expansion leads to the generation of sense and antisense repeat… read more here.
Keywords: bidirectional nucleolar; frontotemporal lobar; repeat; lobar degeneration ... See more keywords