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Insights Into the Bifunctional Aphidicolan-16-ß-ol Synthase Through Rapid Biomolecular Modeling Approaches

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Published in 2018 at "Frontiers in Chemistry"

DOI: 10.3389/fchem.2018.00101

Abstract: Diterpene synthases catalyze complex, multi-step C-C coupling reactions thereby converting the universal, aliphatic precursor geranylgeranyl diphosphate into diverse olefinic macrocylces that form the basis for the structural diversity of the diterpene natural product family. Since… read more here.

Keywords: catalytically relevant; amino acids; cyclization; biomolecular modeling ... See more keywords