Application of the anthraquinone drug rhein as an axial ligand in bifunctional Pt(IV) complexes to obtain antiproliferative agents against human glioblastoma cells.
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DOI: 10.1039/d2dt00235c
Abstract: Octahedral Pt(IV) prodrugs are an effective way to combine cisplatin-like moieties and a second drug to obtain selective and stimuli responsive bifunctional antiproliferative compounds. Recently, two bifunctional Pt(IV) complexes have shown interesting in vitro and… read more here.
Keywords: bifunctional complexes; human glioblastoma; cisplatin; drug ... See more keywords