Assessing the genotoxicity of N‐nitrosodiethylamine with three in vivo endpoints in male Big Blue® transgenic and wild‐type C57BL/6N mice
Sign Up to like & getrecommendations! Published in 2024 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22615
Abstract: The detection of N‐nitrosamines in drug products has raised global regulatory interest in recent years due to the carcinogenic potential of some nitrosamines in animals and a need to identify a testing strategy has emerged.… read more here.
Keywords: mice; c57bl mice; three vivo; big blue ... See more keywords
Discovery of an Unexplored Protein Structural Scaffold of Serine Protease from Big Blue Octopus (Octopus cyanea): A New Prospective Lead Molecule.
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DOI: 10.2174/1570163814666170102141931
Abstract: BACKGROUND Serine proteases are a group of enzymes that hydrolyses the peptide bonds in proteins. In mammals, these enzymes help in the regulation of several major physiological functions such as digestion, blood clotting, responses of… read more here.
Keywords: molecule; octopus; serine protease; serine ... See more keywords
Mutation Analysis in Cultured Cells of Transgenic Rodents
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19010262
Abstract: To comply with guiding principles for the ethical use of animals for experimental research, the field of mutation research has witnessed a shift of interest from large-scale in vivo animal experiments to small-sized in vitro… read more here.
Keywords: transgenic rodents; cultured cells; cells transgenic; analysis ... See more keywords