Articles with "biginelli reactions" as a keyword



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Synthesis of Novel 1,2,3-Triazole-Dihydropyrimidinone Hybrids Using Multicomponent 1,3-Dipolar Cycloaddition (Click)–Biginelli Reactions: Anticancer Activity

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Published in 2020 at "Synlett"

DOI: 10.1055/s-0039-1690781

Abstract: In this work, 21 novel (1,4-disubstituted 1,2,3-triazole)-dihydropyrimidinone (1,2,3-trzl-DHPM) type hybrids were synthesized and characterized. These were divided into two types: hybrids A (5 in total) containing the dihydropyrimidinone heterocyclic ring decorated with a 1,4-disubstituted 1,2,3-triazole… read more here.

Keywords: dihydropyrimidinone; biginelli reactions; cycloaddition; cancer ... See more keywords