Pathway engineering in yeast for synthesizing the complex polyketide bikaverin
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DOI: 10.1038/s41467-020-19984-3
Abstract: Fungal polyketides display remarkable structural diversity and bioactivity, and therefore the biosynthesis and engineering of this large class of molecules is therapeutically significant. Here, we successfully recode, construct and characterize the biosynthetic pathway of bikaverin,… read more here.
Keywords: engineering; bikaverin; pathway engineering; engineering yeast ... See more keywords
Conserved Responses in a War of Small Molecules between a Plant-Pathogenic Bacterium and Fungi
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DOI: 10.1128/mbio.00820-18
Abstract: ABSTRACT Small-molecule signaling is one major mode of communication within the polymicrobial consortium of soil and rhizosphere. While microbial secondary metabolite (SM) production and responses of individual species have been studied extensively, little is known… read more here.
Keywords: fusarium; plant; ralstonia; bikaverin ... See more keywords