The mitotic role of Adenomatous Polyposis Coli requires its bilateral interaction with tubulin and microtubules.
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DOI: 10.1242/jcs.260152
Abstract: Adenomatous Polyposis Coli (APC) is a scaffold protein with tumour suppressor properties. Mutations causing the loss of its C-terminal domain (APC-C) - bearing cytoskeleton-regulating sequences - correlate with colorectal cancer. The cellular roles of APC… read more here.
Keywords: tubulin microtubules; adenomatous polyposis; bilateral interaction; tubulin ... See more keywords