Lipid bilayer stress in obesity‐linked inflammatory and metabolic disorders
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2018.02.022
Abstract: &NA; The maintenance of the characteristic lipid compositions and physicochemical properties of biological membranes is essential for their proper function. Mechanisms allowing to sense and restore membrane homeostasis have been identified in prokaryotes for a… read more here.
Keywords: lipid bilayer; bilayer stress; membrane; obesity ... See more keywords
Reducing lipid bilayer stress by monounsaturated fatty acids protects renal proximal tubules in diabetes
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.74391
Abstract: In diabetic patients, dyslipidemia frequently contributes to organ damage such as diabetic kidney disease (DKD). Dyslipidemia is associated with both excessive deposition of triacylglycerol (TAG) in lipid droplets (LDs) and lipotoxicity. Yet, it is unclear… read more here.
Keywords: renal proximal; stress; bilayer stress; fatty acids ... See more keywords