Alteration in faecal bile acids, gut microbial composition and diversity after laparoscopic sleeve gastrectomy
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Surgery"
DOI: 10.1002/bjs.11654
Abstract: Laparoscopic sleeve gastrectomy (LSG) is a well established treatment for severe obesity and type 2 diabetes. Although the gut microbiota is linked to the efficacy of LSG, the underlying mechanisms remain elusive. The effect of… read more here.
Keywords: laparoscopic sleeve; bile acids; sleeve gastrectomy;
Bile Acids, Gut Microbiome and the Road to Fatty Liver Disease.
Sign Up to like & getrecommendations! Published in 2021 at "Comprehensive Physiology"
DOI: 10.1002/cphy.c210024
Abstract: This article describes the complex interactions occurring between diet, the gut microbiome, and bile acids in the etiology of fatty liver disease. Perhaps 25% of the world's population may have nonalcoholic fatty liver disease (NAFLD)… read more here.
Keywords: liver disease; fatty liver; gut microbiome; bile acids ... See more keywords
Autophagic flux inhibition, apoptosis, and mitochondrial dysfunction in bile acids‐induced impairment of human placental trophoblast
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30774
Abstract: Intrahepatic cholestasis of pregnancy (ICP) is a common pregnancy‐specific disease, characterized by increased bile acid levels and adverse fetal outcomes. We previously reported excessive bile acids led to dysfunction of placental trophoblasts in ICP. However,… read more here.
Keywords: autophagic flux; mitochondrial dysfunction; bile acids; dysfunction ... See more keywords
Phosphatidylglucose Alleviates Atherosclerosis by Increasing Cholesterol Alienation to Bile Acids and Cholesterol Efflux in ApoE-/- Mice.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12626
Abstract: BACKGROUND Phosphatidylcholine (PC) are considered to be the major dietary sources for choline, which is associated with the atherosclerosis progress. Thus, phosphatidylglucose (PG) was prepared by enzymatic modification of PC to study the effects on… read more here.
Keywords: cholesterol alienation; increasing cholesterol; bile acids; cholesterol ... See more keywords
LC-MS/MS Analysis of Bile Acids.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7592-1_8
Abstract: Besides their role as lipid solubilizers, bile acids (BAs) are increasingly appreciated as bioactive molecules. They bind to G-protein-coupled receptors and nuclear hormone receptors. So they control their own metabolism and act on lipid and… read more here.
Keywords: analysis bile; bile acids; biology;
Setup and Use of HepaRG Cells in Cholestasis Research.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9420-5_19
Abstract: Since HepaRG cells can differentiate into well-polarized mature hepatocyte-like cells that synthesize, conjugate, and secrete bile acids, they represent an appropriate surrogate to primary human hepatocytes for investigations on drug-induced cholestasis mechanisms. In this chapter,… read more here.
Keywords: cells cholestasis; bile acids; setup use; heparg cells ... See more keywords
Measuring the Impact of Bile Acids on the Membrane Order of Primary Hepatocytes and Isolated Mitochondria by Fluorescence Imaging and Spectroscopy.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9420-5_7
Abstract: Cholestasis is characterized by impaired secretion of bile flow that can result in the accumulation of highly abnormal levels of bile acids causing hepatocyte and biliary injury. As amphipathic molecules, bile acids can intercalate in… read more here.
Keywords: acids membrane; bile acids; membrane order; fluorescence ... See more keywords
Bile Acid Toxicity and Protein Kinases.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-49844-3_9
Abstract: If the bile acids reach to pathological concentrations due to cholestasis, accumulation of hydrophobic bile acids within the hepatocyte may result in cell death. Thus, hydrophobic bile acids induce apoptosis in hepatocytes, while hydrophilic bile… read more here.
Keywords: bile acids; death; apoptosis; hydrophobic bile ... See more keywords
Influences of Taurine Deficiency on Bile Acids of the Bile in the Cat Model.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-8023-5_4
Abstract: Taurine content in the body is maintained by both biosynthesis from sulfur-contained amino acids in the liver and ingestion from usual foods, mainly seafoods and meat. Contrary to the rodents, the maintenance of taurine content… read more here.
Keywords: bile acids; taurine deficiency; deficiency bile; acids bile ... See more keywords
Evaluating the structural complexity of isomeric bile acids with ion mobility spectrometry
Sign Up to like & getrecommendations! Published in 2019 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-019-01869-0
Abstract: Bile acids (BAs) play an integral role in digestion through the absorption of nutrients, emulsification of fats and fat-soluble vitamins, and maintenance of cholesterol levels. Metabolic disruption, diabetes, colorectal cancer, and numerous other diseases have… read more here.
Keywords: ion mobility; bile acids; mobility spectrometry; spectrometry ... See more keywords
Bile acids and their effects on diabetes
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers of Medicine"
DOI: 10.1007/s11684-018-0644-x
Abstract: Diabetes is a widespread, rapidly increasing metabolic disease that is driven by hyperglycemia. Early glycemic control is of primary importance to avoid vascular complications including development of retinal disorders leading to blindness, end-stage renal disease,… read more here.
Keywords: effects diabetes; bile acids; control; glycemic control ... See more keywords