Concurrent activation of Kras and canonical Wnt signaling induces premalignant lesions that progress to extrahepatic biliary cancer in mice.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer research"
DOI: 10.1158/0008-5472.can-21-2176
Abstract: Biliary cancer has long been known to carry a poor prognosis, yet the molecular pathogenesis of carcinoma of the extrahepatic biliary system and its precursor lesions remains elusive. Here we investigated the role of Kras… read more here.
Keywords: canonical wnt; cancer; biliary cancer; kras canonical ... See more keywords
Mutational landscape and tumor mutation burden (TMB) feature of biliary cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e16670
Abstract: e16670Background: Biliary cancer are relatively rare, highly aggressive and have poor prognoses. Most biliary cancers are diagnosed in the advanced and metastatic stages. Chemotherapy is the main t... read more here.
Keywords: mutational landscape; tumor mutation; cancer; mutation burden ... See more keywords
Identification of antibody against wingless‑type MMTV integration site family member 7B as a biliary cancer tumor marker.
Sign Up to like & getrecommendations! Published in 2022 at "Oncology reports"
DOI: 10.3892/or.2022.8471
Abstract: Biliary cancer has a poor prognosis due to a lack of specific biomarkers and difficulty in diagnosis. The present study aimed to identify serum tumor markers for the diagnosis of biliary cancer via serological identification… read more here.
Keywords: integration site; mmtv integration; biliary cancer; type mmtv ... See more keywords