175 Years of Bilirubin Testing: Ready for Point-of-Care?
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203380
Abstract: Bilirubin is first detected in blood in 1847 and since then has become one of the most widely used biomarkers for liver disease. Clinical routine bilirubin testing is performed at the hospital laboratory, and the… read more here.
Keywords: point care; bilirubin; care; 175 years ... See more keywords
Update on a previously reported missense mutation: The c.1160 C>A mutation in the UGT1A1 gene result in Crigler–Najjar syndrome type 1
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1805
Abstract: To the Editor, Crigler– Najjar syndrome (CN) is a rare inherited disorder with a frequency of one per million. CN is characterized by nonhemolytic unconjugated hyperbilirubinemia. Unconjugated hyperbilirubinemia is caused by the limitation or absence… read more here.
Keywords: 1160 mutation; bilirubin; activity; mutation ... See more keywords
Serum bilirubin is associated with a reduced risk of subsequent recurrent wheezing following acute respiratory syncytial virus bronchiolitis.
Sign Up to like & getrecommendations! Published in 2023 at "Pediatric pulmonology"
DOI: 10.1002/ppul.26493
Abstract: BACKGROUND Bilirubin is a potent antioxidant and anti-inflammatory molecule that has been shown to ameliorate airway inflammation. We aimed to study whether serum bilirubin is protective and can predict the development of subsequent recurrent wheezing… read more here.
Keywords: bilirubin; subsequent recurrent; serum bilirubin; recurrent wheezing ... See more keywords
Bilirubin enzyme biosensor: potentiality and recent advances towards clinical bioanalysis
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology Letters"
DOI: 10.1007/s10529-017-2396-0
Abstract: Bilirubin detection plays a major role in healthcare. Its high concentration in human serum is lethal and must be determined accurately. Clinically, it is vital for assessing patients with deleterious health conditions such as jaundice… read more here.
Keywords: bilirubin detection; bilirubin enzyme; potentiality recent; bilirubin ... See more keywords
Procion Blue H-5R functionalized cellulose membrane with specific removal of bilirubin
Sign Up to like & getrecommendations! Published in 2019 at "Cellulose"
DOI: 10.1007/s10570-019-02660-1
Abstract: The specific removal of bilirubin is essential to cure hyperbilirubinemia. In this study, cellulose membranes were prepared by a phase inversion technique with surface functionalized Procion Blue H-5R (PB) for bilirubin adsorption. The chemical structures… read more here.
Keywords: adsorption; bilirubin; procion blue; removal bilirubin ... See more keywords
If DILI Is Suspected, Don’t Dally
Sign Up to like & getrecommendations! Published in 2021 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-020-06730-4
Abstract: An obese 64-year-old pre-diabetic Navajo woman (BMI: 36) was initially treated for hypoxemic respiratory failure due to interstitial lung disease (ILD) and cryptogenic organizing pneumonia (COP). She was begun on long-term treatment with prednisone 20… read more here.
Keywords: liver; bilirubin; serum; dili suspected ... See more keywords
[Effectiveness and safety of two phototherapy devices for the humanised management of neonatal jaundice].
Sign Up to like & getrecommendations! Published in 2019 at "Anales de pediatria"
DOI: 10.1016/j.anpedi.2019.02.008
Abstract: INTRODUCTION Neonatal jaundice is common, especially in premature infants. Compliance with treatment protocols and standard serum bilirubin curves forces the clinician to separate the child from the mother after birth for short phototherapy. The objective… read more here.
Keywords: effectiveness safety; jaundice; bilirubin; neonatal jaundice ... See more keywords
A questionnaire survey on the efficacy of various treatments for dyskinetic cerebral palsy due to preterm bilirubin encephalopathy
Sign Up to like & getrecommendations! Published in 2020 at "Brain and Development"
DOI: 10.1016/j.braindev.2020.01.006
Abstract: OBJECTIVES Preterm children with severe dyskinetic cerebral palsy due to bilirubin encephalopathy often suffer from marked generalised hypertonus as they age. We performed a questionnaire survey to investigate patient-reported outcomes of treatments for improving their… read more here.
Keywords: cerebral palsy; dyskinetic cerebral; palsy due; bilirubin ... See more keywords
Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide.
Sign Up to like & getrecommendations! Published in 2019 at "Cell chemical biology"
DOI: 10.1016/j.chembiol.2019.07.006
Abstract: Bilirubin is one of the most frequently measured metabolites in medicine, yet its physiologic roles remain unclear. Bilirubin can act as an antioxidant in vitro, but whether its redox activity is physiologically relevant is unclear because… read more here.
Keywords: links heme; bilirubin links; heme metabolism; redox activity ... See more keywords
Robustness of the Reichert Unistat Bilirubinometer for analysis of hemolyzed samples from neonates.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical biochemistry"
DOI: 10.1016/j.clinbiochem.2016.11.012
Abstract: BACKGROUND AND OBJECTIVES Bilirubin is routinely measured in neonates to avoid the irreversible effects of kernicterus. Grossly hemolyzed samples are routinely rejected under the assumption that bilirubin cannot be accurately measured in hemolyzed samples. The… read more here.
Keywords: risk; hemolyzed samples; hemolysis; bilirubin ... See more keywords
Evaluation of vitamin D status bone mineral density and dental health in children with cholestasis.
Sign Up to like & getrecommendations! Published in 2018 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2017.11.010
Abstract: BACKGROUND Hepatic osteodystrophy caused by vitamin D and calcium malabsorption is thought to develop in children with cholestatic liver disease leading to secondary hyperparathyroidism and rickets or osteomalacia. The aim of this study was to… read more here.
Keywords: bone mineral; bilirubin; mineral density; calcium ... See more keywords