Bim contributes to the progression of Huntington's disease-associated phenotypes.
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DOI: 10.1093/hmg/ddz275
Abstract: Huntington's disease (HD) is a neurodegenerative disorder caused by an expanded polyglutamine (polyQ) tract in the huntingtin (HTT) protein. Mutant HTT (mHTT) toxicity is caused by its aggregation/oligomerisation. The striatum is the most vulnerable region,… read more here.
Keywords: associated phenotypes; bim contributes; huntington disease; disease ... See more keywords