Bimodal expression of potential drug target CLL‐1 (CLEC12A) on CD34+ blasts of AML patients
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DOI: 10.1111/ejh.13672
Abstract: This study aims to retrospectively assess C‐lectin‐like molecule 1 (CLL‐1) bimodal expression on CD34+ blasts in acute myeloid leukemia (AML) patients (total N = 306) and explore potential CLL‐1 bimodal associations with leukemia and patient‐specific… read more here.
Keywords: cll; aml patients; bimodal expression; cd34 blasts ... See more keywords
Bacterial-Chromatin Structural Proteins Regulate the Bimodal Expression of the Locus of Enterocyte Effacement (LEE) Pathogenicity Island in Enteropathogenic Escherichia coli
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DOI: 10.1128/mbio.00773-17
Abstract: ABSTRACT In enteropathogenic Escherichia coli (EPEC), the locus of enterocyte effacement (LEE) encodes a type 3 secretion system (T3SS) essential for pathogenesis. This pathogenicity island comprises five major operons (LEE1 to LEE5), with the LEE5… read more here.
Keywords: ler; enteropathogenic escherichia; escherichia coli; bimodal expression ... See more keywords
CD49d promotes disease progression in chronic lymphocytic leukemia: new insights from CD49d bimodal expression.
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DOI: 10.1182/blood.2019003179
Abstract: CD49d is a remarkable prognostic biomarker of chronic lymphocytic leukemia (CLL). The extensively validated 30% of positive CLL cells cut-off value is able to separate CLL patients into two subgroups with different prognosis, but it… read more here.
Keywords: cll; sub population; bimodal expression; cd49d ... See more keywords