A multiplexable TALE-based binary expression system for in vivo cellular interaction studies
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-01592-3
Abstract: Binary expression systems have revolutionised genetic research by enabling delivery of loss-of-function and gain-of-function transgenes with precise spatial-temporal resolution in vivo. However, at present, each existing platform relies on a defined exogenous transcription activator capable… read more here.
Keywords: tale based; system; expression; function ... See more keywords
Propagation of seminal toxins through binary expression gene drives could suppress populations
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-10327-4
Abstract: Gene drives can be highly effective in controlling a target population by disrupting a female fertility gene. To spread across a population, these drives require that disrupted alleles be largely recessive so as not to… read more here.
Keywords: gene drives; binary expression; gene; spread ... See more keywords
Development of a set of novel binary expression vectors for plant gene function analysis and genetic transformation
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.1104905
Abstract: With the advent of multiple omics and Genome-Wide Association Studies (GWAS) technology, genome-scale functional analysis of candidate genes is to be conducted in diverse plant species. Construction of plant binary expression vectors is the prerequisite… read more here.
Keywords: analysis; expression vectors; plant; gene ... See more keywords