Network regression analysis for binary and ordinal categorical phenotypes in transcriptome-wide association studies.
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DOI: 10.1093/genetics/iyac153
Abstract: Transcriptome-wide association studies (TWASs) aim to integrate genome-wide association studies (GWASs) and expression quantitative trait loci (eQTL) mapping studies for exploring the gene regulatory mechanisms underlying diseases. Existing TWAS methods primarily focus on one gene… read more here.
Keywords: ordinal categorical; network; binary ordinal; wide association ... See more keywords