Mg2+ Enhances the Formation of 2′,3′-cGMP, an Intermediate of RNA Cleavage by Binase
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DOI: 10.1007/s12668-016-0302-1
Abstract: Binase, the ribonuclease secreted by Bacillus pumilus, is an endonuclease that cleaves the phosphodiester bond between the 3′-guanyl residue and 5′-OH residue of an adjacent nucleotide, with the formation of a corresponding intermediate, 2′,3′-cGMP on… read more here.
Keywords: cgmp; enhances formation; binase; mg2 enhances ... See more keywords
Ribonuclease from Bacillus Acts as an Antiviral Agent against Negative- and Positive-Sense Single Stranded Human Respiratory RNA Viruses
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DOI: 10.1155/2017/5279065
Abstract: Bacillus pumilus ribonuclease (binase) was shown to be a promising antiviral agent in animal models and cell cultures. However, the mode of its antiviral action remains unknown. To assess the binase effect on intracellular viral… read more here.
Keywords: rna viruses; rna; binase; positive sense ... See more keywords