RNA aptamers targeted for human αA-crystallin do not bind αB-crystallin, and spare the α-crystallin domain.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.07.085
Abstract: The molecular chaperones, α-crystallins, belong to the small heat shock protein (sHSP) family and prevent the aggregation and insolubilization of client proteins. Studies in vivo have shown that the chaperone activity of the α-crystallins is raised… read more here.
Keywords: bind; rna aptamers; aptamers targeted; crystallin ... See more keywords
On the evolution of protein–adenine binding
Sign Up to like & getrecommendations! Published in 2020 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1911349117
Abstract: Significance How proteins evolved to recognize and bind their ligands is a key mystery in protein function evolution. To explore this mystery, we study how proteins bind adenine, an ancient fragment. We characterize physicochemical patterns… read more here.
Keywords: bind; evolution protein; adenine binding; protein adenine ... See more keywords
Potato Virus Y HCPro Suppression of Antiviral Silencing in Nicotiana benthamiana Plants Correlates with Its Ability To Bind In Vivo to 21- and 22-Nucleotide Small RNAs of Viral Sequence
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Virology"
DOI: 10.1128/jvi.00367-17
Abstract: ABSTRACT We have investigated short and small RNAs (sRNAs) that were bound to a biologically active hexahistidine-tagged Potato virus Y (PVY) HCPro suppressor of silencing, expressed from a heterologous virus vector in Nicotiana benthamiana plants,… read more here.
Keywords: hcpro; small rnas; benthamiana plants; bind ... See more keywords
The ability of Lactobacillus rhamnosus to bind patulin and its application in apple juice
Sign Up to like & getrecommendations! Published in 2020 at "Acta Alimentaria"
DOI: 10.1556/066.2020.49.1.12
Abstract: The purpose of this study was to evaluate the ability of Lactobacillus rhamnosus to bind patulin (PAT) in the buffer solution and apple juice. The binding of L. rhamnosus to PAT was reversible, which improved… read more here.
Keywords: bind; rhamnosus; ability; apple juice ... See more keywords