Identification of key amino acid residues determining ligand binding specificity, homodimerization and cellular distribution of human galectin-10
Sign Up to like & getrecommendations! Published in 2019 at "Glycobiology"
DOI: 10.1093/glycob/cwy087
Abstract: Charcot-Leyden crystal protein/Gal-10, abundantly expressed in eosinophils and basophils, is related to several immune diseases. Recently, crystallographic and biochemical studies showed that Gal-10 cannot bind lactose, because a glutamate residue (Glu33) from another monomer blocks… read more here.
Keywords: gal; ligand binding; identification key; distribution ... See more keywords