How Peptides Bind to PSD-95/Discs-Large/ZO-1 Domains.
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DOI: 10.1021/acs.jctc.1c01140
Abstract: PSD-95/discs-large/ZO-1 (PDZ) domains form a large family of adaptor proteins that bind to the C-terminal tails of their binding partner proteins. Via extensive molecular dynamics simulations and alchemical free energy calculations, we characterized the binding… read more here.
Keywords: peptides bind; discs large; free energy; psd discs ... See more keywords