Linking Transthyretin-Binding Chemicals and Free Thyroid Hormones: In Vitro to In Vivo Extrapolation Based on a Competitive Binding Model.
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DOI: 10.1021/acs.est.3c01094
Abstract: Large numbers of pollutants competitively inhibit the binding between thyroid hormones and transthyretin (TTR) in vitro. However, the impact of this unintended binding on free thyroid hormones in vivo has not yet been characterized. Herein,… read more here.
Keywords: binding; ttr binding; free thyroid; binding chemicals ... See more keywords