Differential Impact of Random GC Tetrad Binding and Chromatin Events on Transcriptional Inhibition by Olivomycin A
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DOI: 10.3390/ijms23168871
Abstract: Olivomycin A (OA), an antibiotic of the aureolic acid family, interferes with gene transcription upon forming complexes with GC-rich regions in the DNA minor groove. We demonstrate that the mechanism of transcriptional deregulation is not… read more here.
Keywords: impact random; chromatin events; tetrad binding; binding chromatin ... See more keywords