Autocleavage of separase suppresses its premature activation by promoting binding to cyclin B1.
Sign Up to like & getrecommendations! Published in 2022 at "Cell reports"
DOI: 10.2139/ssrn.4125670
Abstract: Accurate chromosome segregation requires timely activation of separase, a protease that cleaves cohesin during the metaphase-to-anaphase transition. However, the mechanism that maintains the inactivity of separase prior to this event remains unclear. We provide evidence… read more here.
Keywords: separase autocleavage; autocleavage; separase; binding cyclin ... See more keywords