Articles with "binding displacement" as a keyword



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Potential protein-binding displacement interactions with perampanel: An in vitro analysis

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Published in 2019 at "Epilepsy Research"

DOI: 10.1016/j.eplepsyres.2018.12.003

Abstract: Plasma protein binding and effects on volume of distribution and pharmacologically active, circulating-drug concentrations are complex issues. Protein-binding displacement often underlies drug-drug interactions. Perampanel is a once-daily oral anti-seizure drug for focal seizures and primary… read more here.

Keywords: protein; binding displacement; protein binding; plasma ... See more keywords