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Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.44258
Abstract: This cross-sectional study estimates the seroprevalence of antibodies specific to the receptor binding domain of the spike protein of SARS-CoV-2 and vaccination coverage among adults in Los Angeles County, California, in April 2021.
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Keywords:
antibodies specific;
receptor binding;
sars cov;
binding domain ... See more keywords
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Published in 2021 at "Febs Letters"
DOI: 10.1002/1873-3468.14038
Abstract: The pathogenesis of the SARS‐CoV‐2 virus initiates through recognition of the angiotensin‐converting enzyme 2 (ACE2) receptor of the host cells by the receptor‐binding domain (RBD) located at the spikes of the virus. Here, using molecular…
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Keywords:
binding domain;
electrostatics;
receptor;
sars cov ... See more keywords
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Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14541
Abstract: The hybrid binding domain (HBD) is a conserved fold present in ribonucleases H1 that selectively recognizes RNA–DNA hybrids, which are structures present in cellular R‐loops and participate in diverse biological processes. We engineered multivalent HBD…
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Keywords:
rna dna;
hybrid binding;
high affinity;
affinity ... See more keywords
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Published in 2022 at "Journal of clinical laboratory analysis"
DOI: 10.1002/jcla.24306
Abstract: OBJECTIVE Detecting neutralizing antibodies targeting receptor-binding domain (RBD) is important for the assessment of humoral protection and vaccine efficacy after vaccination. We compared the performance of three surrogate immunoassays for detection of neutralizing antibodies targeting…
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Keywords:
binding domain;
comparison;
vaccination;
detection ... See more keywords
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Published in 2023 at "Molecular informatics"
DOI: 10.1002/minf.202300026
Abstract: Androgen receptor (AR) inhibition remains the primary strategy to combat the progression of prostate cancer (PC). However, all clinically used AR inhibitors target the ligand-binding domain (LBD), which is highly susceptible to truncations through splicing…
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Keywords:
novel inhibitors;
virtual screening;
androgen receptor;
ultra large ... See more keywords
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Published in 2017 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-017-2722-7
Abstract: Connexin 43 (Cx43) hemichannels establish local signaling networks via the release of ATP and other molecules, but their excessive opening may result in cell death. Hence, the activity of Cx43-hemichannels ought to be critically controlled.…
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Keywords:
binding domain;
hemichannel activity;
sh3 binding;
cx43 ... See more keywords
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Published in 2017 at "Biomolecular NMR Assignments"
DOI: 10.1007/s12104-017-9755-6
Abstract: Starch binding domains (SBDs) are important for the functions of glycoside hydrolysis enzymes such as α-amylases, they have great application potential in biotechnology and industries. AmyP is a newly identified α-amylase belonging to a new…
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Keywords:
amyp sbd;
binding domain;
starch binding;
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Published in 2017 at "Biomolecular NMR Assignments"
DOI: 10.1007/s12104-017-9760-9
Abstract: Musashi1 (Msi1) is an RNA-binding protein that is involved in cell fate determination. Here, we report the 1H, 15N, and 13C resonance assignments of Msi1 second RNA-binding domain in free form and in complex with…
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Keywords:
binding domain;
form complex;
free form;
rna ... See more keywords
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Published in 2017 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2016.11.003
Abstract: With increasing concerns of estrogenic effects of endocrine disrupting compounds, the development of simple detection assay for these compounds is an ongoing need. Herein, a simple, rapid, and highly sensitive assay for estradiol (E2) detection…
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Keywords:
receptor;
binding domain;
detection;
ligand binding ... See more keywords
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Published in 2019 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2019.01.013
Abstract: ABC transporters are membrane-bound pumps composed of two major domains: the transmembrane domain(s) (TMDs) and the nucleotide-binding domain(s) (NBDs). Sequence analyses of the NBDs of key ABC exporters revealed a residue position within the H-loop…
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Keywords:
abcg family;
binding domain;
nucleotide binding;
family ... See more keywords
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Published in 2020 at "Biochemical and Biophysical Research Communications"
DOI: 10.1016/j.bbrc.2020.10.012
Abstract: Immediately from the outset of the COVID-19 pandemic, researchers from diverse biomedical and biological disciplines have united to study the novel pandemic virus, SARS-CoV-2. The antibody response to SARS-CoV-2 has been a major focus of…
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Keywords:
binding domain;
neutralizing antibodies;
receptor;
sars cov ... See more keywords