Following the tracks: how transcription factor binding dynamics control transcription.
Sign Up to like & getrecommendations! Published in 2022 at "Biophysical journal"
DOI: 10.1016/j.bpj.2022.03.026
Abstract: Transcription, the process of copying genetic information from DNA to messenger RNA, is regulated by sequence-specific DNA binding proteins known as transcription factors (TFs). Recent advances in single-molecule tracking (SMT) technologies have enabled visualization of… read more here.
Keywords: dna; dna binding; following tracks; tracks transcription ... See more keywords
Genome‐wide off‐rates reveal how DNA binding dynamics shape transcription factor function
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DOI: 10.15252/msb.20209885
Abstract: Protein–DNA interactions are dynamic, and these dynamics are an important aspect of chromatin‐associated processes such as transcription or replication. Due to a lack of methods to study on‐ and off‐rates across entire genomes, protein–DNA interaction… read more here.
Keywords: binding dynamics; transcription; factor; transcription factor ... See more keywords
Distinct Binding Dynamics, Sites and Interactions of Fullerene and Fullerenols with Amyloid-β Peptides Revealed by Molecular Dynamics Simulations
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20082048
Abstract: The pathology Alzheimer’s disease (AD) is associated with the self-assembly of amyloid-β (Aβ) peptides into β-sheet enriched fibrillar aggregates. A promising treatment strategy is focused on the inhibition of amyloid fibrillization of Aβ peptide. Fullerene… read more here.
Keywords: c60 c60; binding dynamics; molecular dynamics; amyloid peptides ... See more keywords