Structure-thermodynamics-relationships of hepatitis C viral NS3 protease inhibitors.
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DOI: 10.1016/j.ejmech.2020.112195
Abstract: Thermodynamic parameters were determined for structurally-related inhibitors of HCV NS3 protease to assess how binding entropies and enthalpies vary with incremental changes at the P2 and P3 inhibitor subsites. Changing the heterocyclic substituent at P2… read more here.
Keywords: ns3 protease; affinity; thermodynamics; binding enthalpies ... See more keywords