Docking and molecular dynamics studies on triclosan derivatives binding to FabI
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DOI: 10.1007/s00894-016-3192-9
Abstract: FabI, enoyl-ACP reductase (ENR), is the rate-limiting enzyme in the last step for fatty acids biosynthesis in many bacteria. Triclosan (TCL) is a commercial bactericide, and as a FabI inhibitor, it can depress the substrate… read more here.
Keywords: binding fabi; molecular dynamics; position; docking molecular ... See more keywords