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   Articles with "binding globulin" as a keyword



Corticosteroid-binding globulin, induced in testicular Leydig cells by perfluorooctanoic acid, promotes steroid hormone synthesis

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recommendations! Published in 2018 at "Archives of Toxicology"

DOI: 10.1007/s00204-018-2207-y

Abstract: Perfluorooctanoic acid (PFOA) is an abundant perfluoroalkyl substance widely applied in industrial and consumer products. It is a ubiquitous environmental pollutant and suspected endocrine disruptor. Corticosteroid-binding globulin (CBG) is a monomeric glycoprotein that can bind… read more here.

Keywords: hormone; perfluorooctanoic acid; corticosteroid binding; cbg ... See more keywords

Optimized methods for measuring competitive binding of chemical substances to thyroid hormone distributor proteins transthyretin and thyroxine binding globulin

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recommendations! Published in 2024 at "Archives of Toxicology"

DOI: 10.1007/s00204-024-03842-y

Abstract: Transthyretin (TTR) and thyroxine-binding globulin (TBG) are two major thyroid hormone (TH) distributor proteins in human plasma, playing important roles in stabilizing the TH levels in plasma, delivery of TH to target tissues, and trans-barrier… read more here.

Keywords: distributor proteins; distributor; binding globulin; thyroid hormone ... See more keywords
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Estradiol induces allosteric coupling and partitioning of sex-hormone-binding globulin monomers among conformational states

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recommendations! Published in 2021 at "iScience"

DOI: 10.1016/j.isci.2021.102414

Abstract: Summary Sex-hormone-binding globulin (SHBG) regulates the transport and bioavailability of estradiol. The dynamics of estradiol's binding to SHBG are incompletely understood, although it is believed that estradiol binds to each monomer of SHBG dimer with… read more here.

Keywords: hormone; shbg; estradiol binding; sex hormone ... See more keywords

Serum sex hormone-binding globulin is associated with symptomatic late-onset hypogonadism in aging rural males: a community-based study.

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recommendations! Published in 2021 at "Sexual health"

DOI: 10.1071/sh20201

Abstract: BACKGROUND To investigate whether serum levels of sex hormone-binding globulin (SHBG) and testosterone are associated with symptomatic late-onset hypogonadism (SLOH) in middle-aged and elderly rural Chinese males. METHODS A population-based cross-sectional study was conducted in… read more here.

Keywords: late onset; binding globulin; sex hormone; symptomatic late ... See more keywords

The association between serum sex hormone-binding globulin changes during progestin-primed ovarian stimulation and embryo outcomes: a retrospective cohort study

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recommendations! Published in 2022 at "Gynecological Endocrinology"

DOI: 10.1080/09513590.2022.2112940

Abstract: Abstract Objective: This study is aimed to examine the associations between embryo outcomes and serum sex hormone-binding globulin (SHBG) changes during progestin-primed ovarian stimulation (PPOS) protocols in IVF/ICSI cycles. Research methods: This study included 2790… read more here.

Keywords: hormone binding; embryo outcomes; serum sex; sex hormone ... See more keywords

Sex hormone-binding globulin and thrombin generation in women using hormonal contraception

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recommendations! Published in 2017 at "Biomarkers"

DOI: 10.1080/1354750x.2016.1204010

Abstract: Abstract Objectives: We investigated the impact of serum sex hormone-binding globulin (SHBG) on thrombin generation (TG) in women according to hormonal contraception. Patients and methods: A cross-sectional study of SHBG and TG measured via calibrated… read more here.

Keywords: contraception; thrombin generation; sex hormone; binding globulin ... See more keywords

Association between sex hormone-binding globulin and kidney function in men: results from the SPECT-China study

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recommendations! Published in 2022 at "Chinese Medical Journal"

DOI: 10.1097/cm9.0000000000002046

Abstract: Abstract Background: The association between sex hormone-binding globulin (SHBG) and renal function has rarely been reported in men. We aimed to investigate the above association in a community-based Chinese population. Methods: A total of 5027… read more here.

Keywords: hormone binding; sex hormone; binding globulin; low egfr ... See more keywords
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Sex differences, endogenous sex‐hormone hormones, sex‐hormone binding globulin, and exogenous disruptors in diabetes and related metabolic outcomes

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recommendations! Published in 2018 at "Journal of Diabetes"

DOI: 10.1111/1753-0407.12517

Abstract: In assessing clinical and pathophysiological development of type 2 diabetes (T2D), the critical role of the sex steroids axis is underappreciated, particularly concerning the sex‐specific relationships with many relevant cardiometabolic outcomes. In this issue of… read more here.

Keywords: hormones sex; sex; sex hormone; binding globulin ... See more keywords
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Relationship between dietary carbohydrates intake and circulating sex hormone‐binding globulin levels in postmenopausal women

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recommendations! Published in 2018 at "Journal of Diabetes"

DOI: 10.1111/1753-0407.12550

Abstract: Low circulating levels of sex hormone‐binding globulin (SHBG) have been shown to be a direct and strong risk factor for type 2 diabetes, cardiovascular diseases, and hormone‐dependent cancers, although the relationship between various aspects of… read more here.

Keywords: binding globulin; hormone binding; dietary carbohydrates; sex hormone ... See more keywords

Sex steroids and sex steroid‐binding globulin levels amongst middle‐aged and elderly men and women from general population

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recommendations! Published in 2022 at "European Journal of Clinical Investigation"

DOI: 10.1111/eci.13866

Abstract: Availability of age‐ and sex‐specific reference values for sex steroids and sex steroid‐binding globulin (SHBG) levels allows for appropriate interpretation of research findings and their clinical applications. We report the sex‐specific distribution and reference levels… read more here.

Keywords: steroids sex; steroid binding; sex; binding globulin ... See more keywords

A Mendelian Randomization Study on the Association Between Sex Hormone‐Binding Globulin and Membranous Nephropathy Risk

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recommendations! Published in 2025 at "Nephrology"

DOI: 10.1111/nep.70049

Abstract: Membranous nephropathy (MN) is the leading cause of nephrotic syndrome in adults, with 80% of cases being primary MN of unknown origin. While the influence of sex hormones on chronic kidney disease (CKD) is thoroughly… read more here.

Keywords: membranous nephropathy; binding globulin; sex hormone; hormone binding ... See more keywords