Corticosteroid-binding globulin, induced in testicular Leydig cells by perfluorooctanoic acid, promotes steroid hormone synthesis
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Toxicology"
DOI: 10.1007/s00204-018-2207-y
Abstract: Perfluorooctanoic acid (PFOA) is an abundant perfluoroalkyl substance widely applied in industrial and consumer products. It is a ubiquitous environmental pollutant and suspected endocrine disruptor. Corticosteroid-binding globulin (CBG) is a monomeric glycoprotein that can bind… read more here.
Keywords: hormone; perfluorooctanoic acid; corticosteroid binding; cbg ... See more keywords
Estradiol induces allosteric coupling and partitioning of sex-hormone-binding globulin monomers among conformational states
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DOI: 10.1016/j.isci.2021.102414
Abstract: Summary Sex-hormone-binding globulin (SHBG) regulates the transport and bioavailability of estradiol. The dynamics of estradiol's binding to SHBG are incompletely understood, although it is believed that estradiol binds to each monomer of SHBG dimer with… read more here.
Keywords: hormone; shbg; estradiol binding; sex hormone ... See more keywords
Serum sex hormone-binding globulin is associated with symptomatic late-onset hypogonadism in aging rural males: a community-based study.
Sign Up to like & getrecommendations! Published in 2021 at "Sexual health"
DOI: 10.1071/sh20201
Abstract: BACKGROUND To investigate whether serum levels of sex hormone-binding globulin (SHBG) and testosterone are associated with symptomatic late-onset hypogonadism (SLOH) in middle-aged and elderly rural Chinese males. METHODS A population-based cross-sectional study was conducted in… read more here.
Keywords: late onset; binding globulin; sex hormone; symptomatic late ... See more keywords
The association between serum sex hormone-binding globulin changes during progestin-primed ovarian stimulation and embryo outcomes: a retrospective cohort study
Sign Up to like & getrecommendations! Published in 2022 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2022.2112940
Abstract: Abstract Objective: This study is aimed to examine the associations between embryo outcomes and serum sex hormone-binding globulin (SHBG) changes during progestin-primed ovarian stimulation (PPOS) protocols in IVF/ICSI cycles. Research methods: This study included 2790… read more here.
Keywords: hormone binding; embryo outcomes; serum sex; sex hormone ... See more keywords
Sex hormone-binding globulin and thrombin generation in women using hormonal contraception
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DOI: 10.1080/1354750x.2016.1204010
Abstract: Abstract Objectives: We investigated the impact of serum sex hormone-binding globulin (SHBG) on thrombin generation (TG) in women according to hormonal contraception. Patients and methods: A cross-sectional study of SHBG and TG measured via calibrated… read more here.
Keywords: contraception; thrombin generation; sex hormone; binding globulin ... See more keywords
Association between sex hormone-binding globulin and kidney function in men: results from the SPECT-China study
Sign Up to like & getrecommendations! Published in 2022 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000002046
Abstract: Abstract Background: The association between sex hormone-binding globulin (SHBG) and renal function has rarely been reported in men. We aimed to investigate the above association in a community-based Chinese population. Methods: A total of 5027… read more here.
Keywords: hormone binding; sex hormone; binding globulin; low egfr ... See more keywords
Sex differences, endogenous sex‐hormone hormones, sex‐hormone binding globulin, and exogenous disruptors in diabetes and related metabolic outcomes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Diabetes"
DOI: 10.1111/1753-0407.12517
Abstract: In assessing clinical and pathophysiological development of type 2 diabetes (T2D), the critical role of the sex steroids axis is underappreciated, particularly concerning the sex‐specific relationships with many relevant cardiometabolic outcomes. In this issue of… read more here.
Keywords: hormones sex; sex; sex hormone; binding globulin ... See more keywords
Relationship between dietary carbohydrates intake and circulating sex hormone‐binding globulin levels in postmenopausal women
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Diabetes"
DOI: 10.1111/1753-0407.12550
Abstract: Low circulating levels of sex hormone‐binding globulin (SHBG) have been shown to be a direct and strong risk factor for type 2 diabetes, cardiovascular diseases, and hormone‐dependent cancers, although the relationship between various aspects of… read more here.
Keywords: binding globulin; hormone binding; dietary carbohydrates; sex hormone ... See more keywords
Sex steroids and sex steroid‐binding globulin levels amongst middle‐aged and elderly men and women from general population
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DOI: 10.1111/eci.13866
Abstract: Availability of age‐ and sex‐specific reference values for sex steroids and sex steroid‐binding globulin (SHBG) levels allows for appropriate interpretation of research findings and their clinical applications. We report the sex‐specific distribution and reference levels… read more here.
Keywords: steroids sex; steroid binding; sex; binding globulin ... See more keywords
Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages
Sign Up to like & getrecommendations! Published in 2018 at "Mediators of Inflammation"
DOI: 10.1155/2018/3062319
Abstract: Sex hormone-binding globulin (SHBG) is a serum protein released mainly by the liver, and a low serum level correlates with a risk for metabolic syndrome including diabetes, obesity, and cardiovascular events. However, the underlying molecular… read more here.
Keywords: sex hormone; adipocytes macrophages; metabolic syndrome; binding globulin ... See more keywords
Detecting Congenital Central Hypothyroidism by Newborn Screening: Difficulty in Distinguishing from Congenital Thyroxine-Binding Globulin Deficiency
Sign Up to like & getrecommendations! Published in 2017 at "Hormone Research in Paediatrics"
DOI: 10.1159/000479367
Abstract: Background/Aims: Congenital central hypothyroidism (CH-C) can be detected on newborn screening (NBS) by programs using thyroxine (T4)-reflex thyroid-stimulating hormone (TSH) test approach. CH-C must be distinguished from T4-binding globulin (TBG) deficiency. We sought to determine… read more here.
Keywords: central hypothyroidism; congenital central; binding globulin; tbg deficiency ... See more keywords