A cell-free approach to identify binding hotspots in plant immune receptors
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DOI: 10.1038/s41598-021-04259-8
Abstract: Plant immune receptors are often difficult to express heterologously, hindering study of direct interactions between these receptors and their targets with traditional biochemical approaches. The cell-free method ribosome display (RD) enables expression of such recalcitrant… read more here.
Keywords: immune receptors; cell free; binding hotspots; plant immune ... See more keywords
An ensemble approach to predict binding hotspots in protein-RNA interactions based on SMOTE data balancing and Random Grouping feature selection strategies
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac138
Abstract: MOTIVATION The identification of binding hotspots in protein-RNA interactions is crucial for understanding their potential recognition mechanisms and drug design. The experimental methods have many limitations, since they are usually time-consuming and labor-intensive. Thus, developing… read more here.
Keywords: binding hotspots; random grouping; protein rna; hotspots protein ... See more keywords