Development of a Novel σ1 Receptor Biosensor Based on Its Heterodimerization with Binding Immunoglobulin Protein in Living Cells.
Sign Up to like & getrecommendations! Published in 2023 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.3c00206
Abstract: The σ1 receptor (S1R) is a ligand-regulated non-opioid intracellular receptor involved in several pathological conditions. The development of S1R-based drugs as therapeutic agents is a challenge due to the lack of simple functional assays to… read more here.
Keywords: s1r; heterodimerization; binding immunoglobulin; s1r bip ... See more keywords
Sialic acid‐binding immunoglobulin‐like lectin (Sigelac)‐15 is a rapidly internalised cell‐surface antigen expressed by acute myeloid leukaemia cells
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Haematology"
DOI: 10.1111/bjh.17496
Abstract: Sialic acid‐binding immunoglobulin‐like lectin (Siglec)‐15 has recently been identified as a critical tumour checkpoint, augmenting the expression and function of programmed death‐ligand 1. We raised a monoclonal antibody, A9E8, specific for Siglec‐15 using phage display.… read more here.
Keywords: immunoglobulin like; myeloid leukaemia; binding immunoglobulin; acid binding ... See more keywords
Binding immunoglobulin 2 functions as a proviral factor for potyvirus infections in Nicotiana benthamiana
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Plant Pathology"
DOI: 10.1111/mpp.13284
Abstract: Abstract Infection of viruses from the genera Bromovirus, Potyvirus, and Potexvirus in Nicotiana benthamiana induces significant up‐regulation of the genes that encode the HSP70 family, including binding immunoglobulin protein 2 (BiP2). Three up‐regulated genes were… read more here.
Keywords: bip2; infection; potyvirus; factor ... See more keywords