Dynamics and binding interactions of peptide inhibitors of dengue virus entry
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biological Physics"
DOI: 10.1007/s10867-018-9515-6
Abstract: In this study, we investigate the binding interactions of two synthetic antiviral peptides (DET2 and DET4) on type II dengue virus (DENV2) envelope protein domain III. These two antiviral peptides are designed based on the… read more here.
Keywords: dengue virus; dynamics binding; binding site; binding interactions ... See more keywords
Binding interactions of a series of sulfonated water-soluble resorcinarenes with bovine liver catalase.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.07.197
Abstract: Resorcinarenes are macrocyclic molecules that can bind different molecules in a supramolecular fashion. There are some sulfonated water-soluble derivatives that have been investigated to bind proteins avoiding fibrillation. The interaction with enzymes such as catalase… read more here.
Keywords: series sulfonated; sulfonated water; interactions series; water soluble ... See more keywords
Elucidation of binding interactions and mechanism of Fludarabine with dsDNA via multispectroscopic and molecular docking studies.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2019.112994
Abstract: Fludarabine is a purine derivative, anti-neoplastic drug and is still being used in the treatments of chronic lymphocytic leukemia, small lymphocytic lymphoma, acute myeloid leukemia, Non-Hodgkin's lymphoma. It achieves its function by interacting with DNA.… read more here.
Keywords: via multispectroscopic; dna; docking studies; spectroscopy ... See more keywords
Study of the binding interactions between uric acid and bovine serum albumin using multiple spectroscopic techniques
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2018.12.026
Abstract: Abstract The binding interactions between bovine serum albumin (BSA) and a large excess of uric acid (UA) have been analyzed in aqueous solution at pH = 7.4, using UV–vis absorption and steady-state, time-resolved, synchronous and three-dimensional fluorescence… read more here.
Keywords: study binding; serum albumin; fluorescence; uric acid ... See more keywords
Synthesis, crystal structure and DNA binding interactions of ethyl 2-(2-acetamidothiazol-4-yl) acetate: Theoretical and experimental investigations
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2019.126903
Abstract: Abstract The present study describes the efficient synthesis, structural characterization and DNA binding interactions of ethyl 2-(2-acetamidothiazol-4-yl)acetate 2. Theoretically and experimentally determined bond lengths, angles and DNA binding interactions are compared. The chemical structure of… read more here.
Keywords: dna binding; dna; ethyl acetamidothiazol; spectroscopy ... See more keywords
Comparative investigation of binding interactions with three steroidal derivatives of d(GGGT)4 G-quadruplex aptamer
Sign Up to like & getrecommendations! Published in 2018 at "Steroids"
DOI: 10.1016/j.steroids.2018.02.003
Abstract: &NA; Steroidal derivatives have attracted tremendous attentions in biological and biomedical areas, due to their variety biological activities. The investigation of structural influences helps in understanding their biological activities. The interactions of steroidal derivatives with… read more here.
Keywords: quadruplex aptamer; steroidal derivatives; three steroidal; gggt quadruplex ... See more keywords
Deciphering Binding Interactions of IL-23R with HDX-MS: Mapping Protein and Macrocyclic Dodecapeptide Ligands.
Sign Up to like & getrecommendations! Published in 2018 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.8b00255
Abstract: Molecular characterization of the binding epitope of IL-23R and its cognate cytokine IL-23 is paramount to understand the role in autoimmune diseases and to support the discovery of new inhibitors of this protein-protein interaction. Our… read more here.
Keywords: interactions 23r; hdx mapping; 23r hdx; deciphering binding ... See more keywords
Abstract 3844: A biophysical investigation into the binding interactions of novel anti-cancer inhibitors of atypical protein kinase C (aPKCs)
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3844
Abstract: The aim of this study is to address the challenge of the expression of recombinant atypical protein kinase C (aPKCs) in a bacterial system and understand the binding interactions of novel anti-cancer inhibitors of aPKCs.… read more here.
Keywords: protein kinase; anti cancer; novel anti; binding interactions ... See more keywords
Binding Interactions of Zinc Cationic Porphyrin with Duplex DNA: From B-DNA to Z-DNA
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19041071
Abstract: Recognition of unusual left-handed Z-DNA by specific binding of small molecules is crucial for understanding biological functions in which this particular structure participates. Recent investigations indicate that zinc cationic porphyrin (ZnTMPyP4) is promising as a… read more here.
Keywords: cationic porphyrin; dna; zinc cationic; dna dna ... See more keywords
Binding Interactions of Peptide Aptamers
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25246055
Abstract: Peptide aptamers are short amino acid chains that are capable of binding specifically to ligands in the same way as their much larger counterparts, antibodies. Ligands of therapeutic interest that can be targeted are other… read more here.
Keywords: peptide aptamers; interactions peptide; binding interactions;