Noncanonical binding of Lck to CD3ε promotes TCR signaling and CAR function
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DOI: 10.1038/s41590-020-0732-3
Abstract: Initiation of T cell antigen receptor (TCR) signaling involves phosphorylation of CD3 cytoplasmic tails by the tyrosine kinase Lck. How Lck is recruited to the TCR to initiate signaling is not well known. We report… read more here.
Keywords: cd3; lck; function; binding lck ... See more keywords