Glycan-Functionalized Microgels for Scavenging and Specific Binding of Lectins.
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DOI: 10.1021/acs.biomac.6b01754
Abstract: Lectins are proteins with a well-defined carbohydrate recognition domain. Many microbial proteins such as bacterial toxins possess lectin or lectin-like binding domains to interact with cell membranes that are decorated with glycan recognition motifs. We… read more here.
Keywords: specific binding; scavenging specific; glycan functionalized; functionalized microgels ... See more keywords
Gb3-binding lectins as potential carriers for transcellular drug delivery
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DOI: 10.1080/17425247.2017.1266327
Abstract: ABSTRACT Objectives: Epithelial cell layers as well as endothelia forming the blood-brain barrier can drastically reduce the efficiency of drug targeting. Our goal was to investigate lectins recognizing the glycosphingolipid globotriaosylceramide (Gb3) for their potential… read more here.
Keywords: drug; drug delivery; gb3 binding; binding lectins ... See more keywords
Sugar-Binding Profiles of Chitin-Binding Lectins from the Hevein Family: A Comprehensive Study
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DOI: 10.3390/ijms18061160
Abstract: Chitin-binding lectins form the hevein family in plants, which are defined by the presence of single or multiple structurally conserved GlcNAc (N-acetylglucosamine)-binding domains. Although they have been used as probes for chito-oligosaccharides, their detailed specificities… read more here.
Keywords: binding lectins; hevein family; chitin binding; affinity ... See more keywords