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Published in 2022 at "Metabolites"
DOI: 10.3390/metabo12121269
Abstract: The investigation of liver-related metabolic stability of a drug candidate is a widely used key strategy in early-stage drug discovery. Metalloporphyrin-based biomimetic catalysts are good and well-described models of the function of CyP450 in hepatocytes.…
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Keywords:
binding linkers;
effect binding;
linkers efficiency;
metalloporphyrin ... See more keywords