Dual threshold optimization and network inference reveal convergent evidence from TF binding locations and TF perturbation responses.
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DOI: 10.1101/gr.259655.119
Abstract: A high-confidence map of the direct, functional targets of each transcription factor (TF) requires convergent evidence from independent sources. Two significant sources of evidence are TF binding locations and the transcriptional responses to direct TF… read more here.
Keywords: threshold optimization; network; binding locations; evidence ... See more keywords