The role of telomere binding molecules for normal and abnormal hematopoiesis
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Hematology"
DOI: 10.1007/s12185-018-2432-4
Abstract: In order to maintain the homeostasis of the hematopoietic system, hematopoietic stem cells (HSCs) need to be maintained while slowly dividing over their lifetime. However, repeated cell divisions lead to the gradual accumulation of DNA… read more here.
Keywords: role telomere; normal abnormal; role; binding molecules ... See more keywords
Discovery of Nucleic Acid Binding Molecules from Combinatorial Biohybrid Nucleobase Peptide Libraries.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c08964
Abstract: Nature has three biopolymers: oligonucleotides, polypeptides, and oligosaccharides. Each biopolymer has independent functions, but when needed, they form mixed assemblies for higher-order purposes, as in the case of ribosomal protein synthesis. Rather than forming large… read more here.
Keywords: discovery nucleic; discovery; molecules combinatorial; acid binding ... See more keywords
Biochemical interactions between LPS and LPS-binding molecules
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DOI: 10.1080/07388551.2019.1709797
Abstract: Abstract Lipopolysaccharide (LPS), the major component of the outer membrane of Gram-negative bacteria, often pose a serious risk not only when delivered in the bloodstream but also in air, the environment and several industrial fields… read more here.
Keywords: biochemical interactions; lps binding; interactions lps; affinity ... See more keywords
Modulating the chemo-mechanical response of structured DNA assemblies through binding molecules
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab1119
Abstract: Abstract Recent advances in DNA nanotechnology led the fabrication and utilization of various DNA assemblies, but the development of a method to control their global shapes and mechanical flexibilities with high efficiency and repeatability is… read more here.
Keywords: dna; binding molecules; dna assemblies; mechanical response ... See more keywords
HIV-1 capsid variability: viral exploitation and evasion of capsid-binding molecules
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DOI: 10.1186/s12977-021-00577-x
Abstract: The HIV-1 capsid, a conical shell encasing viral nucleoprotein complexes, is involved in multiple post-entry processes during viral replication. Many host factors can directly bind to the HIV-1 capsid protein (CA) and either promote or… read more here.
Keywords: hiv capsid; capsid binding; binding molecules; capsid ... See more keywords