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Published in 2020 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.0c01501
Abstract: Only 15% of human kinases carry a bulky residue at the DFG-1 position, providing an opportunity for the design of selective ATP-site inhibitors without the typical hinge-binding interactions. The low sequence homology among unrelated kinases…
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Keywords:
dfg binding;
kinase;
binding new;
new residue ... See more keywords
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Published in 2019 at "Soft matter"
DOI: 10.1039/c9sm01138b
Abstract: This work presents well-defined and switchable micelles of block copolymers consisting of the two anionic polyelectrolytes sodium polyacrylate (NaPA) and sodium polystyrene sulfonate (NaPSS). Micellization occurs due to the specific binding of Ca2+ to acrylate…
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Keywords:
two anionic;
block;
binding new;
micellization ... See more keywords