Synthesis, Antioxidant Activity, and Determination of Binding Parameters of Meso-Tetra-4-Actophenyl-Porphyrin and its Palladium (II) Complex with Superoxide Anion Radicals
Sign Up to like & getrecommendations! Published in 2020 at "Current Bioactive Compounds"
DOI: 10.2174/1573407215666191017105239
Abstract: Meso-tetra-4-actophenyl-porphyrin (TAcPPH2) was synthesized by reacting 4- acetyl-benzaldehyde with pyrrole in propionic acid, and used as a ligand for the synthesis of palladium (II) complex (PdTAcPP). The structure of the ligand and the complex were… read more here.
Keywords: antioxidant activity; binding parameters; meso tetra; tetra actophenyl ... See more keywords
Binding Parameters of [11C]MPC-6827, a Microtubule-Imaging PET Radiopharmaceutical in Rodents
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DOI: 10.3390/ph16040495
Abstract: Impairment and/or destabilization of neuronal microtubules (MTs) resulting from hyper-phosphorylation of the tau proteins is implicated in many pathologies, including Alzheimer’s disease (AD), Parkinson’s disease and other neurological disorders. Increasing scientific evidence indicates that MT-stabilizing… read more here.
Keywords: mpc 6827; 11c mpc; brain; binding parameters ... See more keywords
Estimation of kinetic and thermodynamic ligand-binding parameters using computational strategies.
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DOI: 10.4155/fmc-2016-0224
Abstract: Kinetic and thermodynamic ligand-protein binding parameters are gaining growing importance as key information to consider in drug discovery. The determination of the molecular structures, using particularly x-ray and NMR techniques, is crucial for understanding how… read more here.
Keywords: computational strategies; thermodynamic ligand; binding parameters; ligand protein ... See more keywords