Differential binding patterns of anti-sulfatide antibodies to glial membranes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2018.07.004
Abstract: Sulfatide is a major glycosphingolipid in myelin and a target for autoantibodies in autoimmune neuropathies. However neuropathy disease models have not been widely established, in part because currently available monoclonal antibodies to sulfatide may not… read more here.
Keywords: sulfatide antibodies; patterns anti; binding patterns; differential binding ... See more keywords
Synthetic O-Acetyl-N-glycolylneuraminic Acid Oligosaccharides Reveal Host-Associated Binding Patterns of Coronaviral Glycoproteins.
Sign Up to like & getrecommendations! Published in 2022 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.2c00046
Abstract: A panel of O-acetylated N-glycolylneuraminic acid oligosaccharides has been prepared by diversification of common synthetic precursors by regioselective de-O-acetylation by coronaviral hemagglutinin-esterase (HE) combined with C7-to-C9 acetyl ester migration. The resulting compound library was printed… read more here.
Keywords: acid oligosaccharides; host; binding patterns; glycolylneuraminic acid ... See more keywords
Channelrhodopsins with distinct chromophores and binding patterns
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-51811-x
Abstract: Channelrhodopsins are popular optogenetic tools in neuroscience, but remain poorly understood mechanistically. Here we report the cryo-EM structures of channelrhodopsin-2 (ChR2) from Chlamydomonas reinhardtii and H. catenoides kalium channelrhodopsin (KCR1). We show that ChR2 recruits… read more here.
Keywords: kcr1; binding patterns; patterns channelrhodopsins; distinct chromophores ... See more keywords