Binding and Reactivity of Copper to R1 and R3 Fragments of tau Protein.
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DOI: 10.1021/acs.inorgchem.9b02266
Abstract: Tau protein is present in significant amounts in neurons, where it contributes to the stabilization of microtubules. Insoluble neurofibrillary tangles of tau are associated with several neurological disorders known as tauopathies, among which is Alzheimer's… read more here.
Keywords: reactivity copper; copper complex; binding reactivity; copper ... See more keywords
Role of the Cysteine in R3 Tau Peptide in Copper Binding and Reactivity
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DOI: 10.3390/ijms231810726
Abstract: Tau is a widespread neuroprotein that regulates the cytoskeleton assembly. In some neurological disorders, known as tauopathies, tau is dissociated from the microtubule and forms insoluble neurofibrillary tangles. Tau comprises four pseudorepeats (R1–R4), containing one… read more here.
Keywords: copper; tau; role; binding reactivity ... See more keywords