The architecture of responsive polymeric ligands on protein binding and recovery
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DOI: 10.1039/c7ra01499f
Abstract: Ligand design and optimization are critical for protein purification during downstream processing. Here the effects of three dimensional architecture of salt- and thermo-responsive polymeric ligands on binding and recovery of bovine serum albumin (BSA) were… read more here.
Keywords: recovery; protein binding; responsive polymeric; polymeric ligands ... See more keywords
Ion-specificity in protein binding and recovery for the responsive hydrophobic poly(vinylcaprolactam) ligand
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DOI: 10.1039/c7ra06022j
Abstract: The conformational switch between the hydrophobic state and hydrophilic state of thermo-responsive poly(vinylcaprolactam) (PVCL) has great potential for protein binding and elution applications during protein purification as a hydrophobic interaction chromatography ligand. The lower critical… read more here.
Keywords: protein binding; binding recovery; hydrophobic; poly vinylcaprolactam ... See more keywords