Water-soluble trehalose glycolipids show superior Mincle binding and signaling but impaired phagocytosis and IL-1β production
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.1015210
Abstract: The tremendous potential of trehalose glycolipids as vaccine adjuvants has incentivized the study of how the structures of these ligands relate to their Mincle-mediated agonist activities. Despite this, structure-activity work in the field has been… read more here.
Keywords: binding signaling; mincle; trehalose glycolipids; mincle binding ... See more keywords
Ligand Binding and Signaling of HARE/Stabilin-2
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DOI: 10.3390/biom9070273
Abstract: The Stabilin receptors are a two-member family in the type H class of scavenger receptors. These dynamic receptors bind and internalize multiple ligands from the cell surface for the purpose of clearing extracellular material including… read more here.
Keywords: stabilin; ligand binding; hare stabilin; signaling hare ... See more keywords