A Commercial Non-Binding Surface Effectively Reduces Fibrinogen Adsorption but Does Not Prevent Platelet Adhesion to Fibrinogen.
Sign Up to like & getrecommendations! Published in 2023 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202300052
Abstract: A commercial non-binding surface effectively prevents protein adsorption, however, the platelet phenotype on this surface has yet to be defined. This study evaluates platelet adhesion and adsorption of several plasma/extra-cellular matrix (ECM) proteins to the… read more here.
Keywords: binding surface; adsorption; fibrinogen; platelet adhesion ... See more keywords
Rigid fusions of designed helical repeat binding proteins efficiently protect a binding surface from crystal contacts
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-52121-9
Abstract: Designed armadillo repeat proteins (dArmRPs) bind extended peptides in a modular way. The consensus version recognises alternating arginines and lysines, with one dipeptide per repeat. For generating new binding specificities, the rapid and robust analysis… read more here.
Keywords: binding surface; binding proteins; repeat; surface crystal ... See more keywords