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Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09333-4
Abstract: G-protein-gated inward rectifying potassium channels (GIRKs) require Gβγ subunits and phosphorylated phosphatidylinositides (PIPs) for gating. Although studies have provided insight into these interactions, the mechanism of how these events are modulated by Gβγ and the…
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Keywords:
potassium;
small molecule;
toxin phosphatidylinositides;
binding toxin ... See more keywords