Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes
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DOI: 10.1093/nar/gkx509
Abstract: Abstract The glucocorticoid receptor (GR) is a ligand-regulated transcription factor that controls the expression of extensive gene networks, driving both up- and down-regulation. GR utilizes multiple DNA-binding-dependent and -independent mechanisms to achieve context-specific transcriptional outcomes.… read more here.
Keywords: protein; inflammatory genes; dna binding; binds directly ... See more keywords