MT1-MMP Binds Membranes by Opposite Tips of Its β Propeller to Position It for Pericellular Proteolysis.
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DOI: 10.1016/j.str.2018.10.008
Abstract: Critical to migration of tumor cells and endothelial cells is the proteolytic attack of membrane type 1 matrix metalloproteinase (MT1-MMP) upon collagen, growth factors, and receptors at cell surfaces. Lipid bilayer interactions of the substrate-binding… read more here.
Keywords: proteolysis; mt1 mmp; mmp; binds membranes ... See more keywords
MT1-MMP Binds Membranes by Opposite Tips of Its beta Propeller to Position It for Pericellular Proteolysis.
Sign Up to like & getrecommendations! Published in 2018 at "Structure"
DOI: 10.2210/pdb6clz/pdb
Abstract: Summary Critical to migration of tumor cells and endothelial cells is the proteolytic attack of membrane type 1 matrix metalloproteinase (MT1-MMP) upon collagen, growth factors, and receptors at cell surfaces. Lipid bilayer interactions of the… read more here.
Keywords: proteolysis; mt1 mmp; mmp; binds membranes ... See more keywords