Articles with "bini" as a keyword



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Abstract CT069: Randomized phase 3 study (STARBOARD) evaluating encorafenib (enco) + binimetinib (bini) + pembrolizumab (pembro) for first-line treatment of unresectable locally advanced or metastatic BRAF V600-mutant melanoma

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-ct069

Abstract: Background BRAF V600 mutations are frequently found in metastatic melanoma. This mutation constitutively activates the MAPK pathway, which leads to melanoma progression. Patients with BRAF V600-mutant metastatic melanoma typically receive BRAF inhibitors (BRAFi) + MEK… read more here.

Keywords: bini; v600 mutant; braf v600; melanoma ... See more keywords