Extracellular Vesicles Functional “Brick‐Cement” Bio‐Integrated System for Annulus Fibrosus Repair
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DOI: 10.1002/adfm.202400066
Abstract: Due to the deficiency of mechanical supporting after discectomy and weak proliferative capacity of annulus fibrosus (AF) cells, the AF defect repair remains a clinical challenge. Herein, a myofibroblasts derived extracellular vesicles (M‐EVs) functional “brick‐cement”… read more here.
Keywords: extracellular vesicles; annulus fibrosus; bio; repair ... See more keywords
NSCs Migration Promoted and Drug Delivered Exosomes-Collagen Scaffold via a Bio-Specific Peptide for One-Step Spinal Cord Injury Repair.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202001896
Abstract: Spinal cord injury (SCI) is plaguing medical professionals globally due to the complexity of injury progression. Based on tissue engineering technology, there recently emerges a promising way by integrating drugs with suitable scaffold biomaterials to… read more here.
Keywords: exosomes collagen; cord; migration; collagen scaffold ... See more keywords
Engineering (Bio)Materials through Shrinkage and Expansion.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202100380
Abstract: Although various (bio)fabrication technologies have achieved revolutionary progress in the past decades, engineered constructs still fall short of expectations owing to their inability to attain precisely designable functions. Shrinkable and expandable (bio)materials feature unique characteristics… read more here.
Keywords: bio; bio materials; size shape; shape shifting ... See more keywords
Bio‐Nano Innovations Targeting the Neurovascular Complex for Epilepsy Treatment
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DOI: 10.1002/adhm.202404857
Abstract: Epilepsy is a prevalent chronic neurological disorder characterized by seizures resulting from an imbalance between excitatory and inhibitory neurons. While pharmacotherapy remains the standard treatment, traditional pharmacotherapy faces significant challenges, including poor brain penetration, high… read more here.
Keywords: treatment; epilepsy treatment; bio; epilepsy ... See more keywords
Microfluidic Tissue Engineering and Bio‐Actuation
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DOI: 10.1002/adma.202108427
Abstract: Bio‐hybrid technologies aim to replicate the unique capabilities of biological systems that could surpass advanced artificial technologies. Soft bio‐hybrid robots consist of synthetic and living materials and have the potential to self‐assemble, regenerate, work autonomously,… read more here.
Keywords: bio hybrid; microfluidic tissue; bio; bio actuation ... See more keywords
Self‐Adhesive and Self‐Sustainable Bioelectronic Patch for Physiological Feedback Electronic Modulation of Soft Organs
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Materials"
DOI: 10.1002/adma.202406636
Abstract: Bionic electrical stimulation (Bio‐ES) aims to achieve personalized therapy and proprioceptive adaptation by mimicking natural neural signatures of the body, while current Bio‐ES devices are reliant on complex sensing and computational simulation systems, thus often… read more here.
Keywords: patch; bioelectronic patch; bio; self sustainable ... See more keywords
Zwitterionic Brush‐Grafted Interfacial Bio‐Lubricant Evades Complement C3‐Mediated Macrophage Phagocytosis for Osteoarthritis Therapy
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DOI: 10.1002/adma.202501137
Abstract: Administering a bio‐lubricant is a promising therapeutic approach for the treatment of osteoarthritis (OA), in particular, if it can both manage symptoms and halt disease progression. However, the clearance of these bio‐lubricants mediated by synovial… read more here.
Keywords: bio lubricant; macrophage phagocytosis; bio; macrophage ... See more keywords
A High‐Performance Bio‐Adhesive Using Hyperbranched Aminated Soybean Polysaccharide and Bio‐Based Epoxide
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DOI: 10.1002/admi.202000148
Abstract: Wood adhesives fabricated from biomass can substitute formaldehyde‐based ones, reducing the consumption of fossil resources and eliminating formaldehyde pollution. In this study, a novel and sustainable water‐soluble soybean polysaccharide (WSSPS)‐based adhesive is designed. Specifically, a… read more here.
Keywords: soybean; soybean polysaccharide; bio based; hyperbranched aminated ... See more keywords
Smart Internal Bio‐Glues
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DOI: 10.1002/advs.202203587
Abstract: Although smart bio‐glues have been well documented, the development of internal bio‐glues for non‐invasive or minimally invasive surgery is still met with profound challenges such as safety risk and the lack of deep tissue penetration… read more here.
Keywords: smart internal; bio; internal bio; bio glues ... See more keywords
Microenvironment Restruction of Emerging 2D Materials and their Roles in Therapeutic and Diagnostic Nano-Bio-Platforms.
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DOI: 10.1002/advs.202207759
Abstract: Engineering advanced therapeutic and diagnostic nano-bio-platforms (NBPFs) have emerged as rapidly-developed pathways against a wide range of challenges in antitumor, antipathogen, tissue regeneration, bioimaging, and biosensing applications. Emerged 2D materials have attracted extensive scientific interest… read more here.
Keywords: therapeutic diagnostic; emerging materials; bio platforms; diagnostic nano ... See more keywords
Multi-Functional Bio-HJzyme: Revolutionizing Diabetic Skin Regeneration with its Glucose-Unlocked Sterilization and Programmed Anti-Inflammatory Effects.
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DOI: 10.1002/advs.202300986
Abstract: Antibacterial dynamic therapy (ADT) triggered by reactive oxygen species (ROS) is promising for diabetic infectious disease treatment. However, the limited local O2 /H2 O2 production and post-treatment inflammation remain long-standing issues. To address these challenges,… read more here.
Keywords: bio hjzyme; skin; anti inflammatory; mimetic activity ... See more keywords