Evaluation of Bio-relevant Mouth-Throat Models for Characterization of Metered Dose Inhalers
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DOI: 10.1208/s12249-019-1339-6
Abstract: For inhalation drug characterization, the traditionally used USP induction port provides limited in vivo predictive capability because it does not adequately mimic airway geometry. In this study, various bio-relevant mouth-throat (MT) models, including Alberta Idealized… read more here.
Keywords: mdi; throat; relevant mouth; geometry ... See more keywords
PhysioCell^®; — a Novel, Bio-relevant Dissolution Apparatus: Hydrodynamic Conditions and Factors Influencing the Dissolution Dynamics
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DOI: 10.1208/s12249-022-02494-4
Abstract: The physiologically relevant dissolution apparatuses simulate various aspects of gastrointestinal physiology and help to understand and predict the in vivo behavior of an oral dosage form. In this paper, we present and characterize for the… read more here.
Keywords: bio relevant; dissolution; relevant dissolution; novel bio ... See more keywords
Equilibrium Studies on Pd(II)–Amine Complexes with Bio-Relevant Ligands in Reference to Their Antitumor Activity
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DOI: 10.3390/ijms24054843
Abstract: This review article presents an overview of the equilibrium studies on Pd-amine complexes with bio-relevant ligands in reference to their antitumor activity. Pd(II) complexes with amines of different functional groups, were synthesized and characterized in… read more here.
Keywords: antitumor; equilibrium studies; bio relevant; relevant ligands ... See more keywords